After completing a residency in pediatrics and one in preventive medicine at Johns Hopkins, I started a practice for my neighborhood of Williamsburg, Brooklyn in September 2007. People would visit my website; see my Google calendar; choose a time and input their symptoms; my iphone would alert me; I would make a house call; they'd pay me via Paypal; and we'd follow up by email, IM, videochat, or in person.

Fast Company calls me The Doctor of the Future. I've got a design and consulting firm called The Future Well. Read more about me here.

  • jstn:

Robot and Frank is the feature film debut of Jake Schreier, my friend and longtime Francis and the Lights co-conspirator (you may know him as the director of the incredible video for The Top). It stars Frank Langella as an old man with a slipping memory whose kids (James Marsden and Liv Tyler) give him a caretaker robot that he initially loathes but gradually forms an uneasy alliance with. It just premiered at Sundance this week (see some clips here) and will likely be coming soon to a theater near you.
It also features a number of near-future devices with fictional user interfaces imagined and designed by myself, which was one of the funnest projects I’ve ever worked on. I have a new appreciation for the needs of a real, functioning interface versus the kind you see in the movies. I don’t want to spoil anything, but if you wind up seeing it keep an eye on Frank’s TV and everyone’s cell phones and tablets.
So, clearly I’m biased, but I saw a rough cut of the movie a couple months back and truly loved it. I couldn’t be more proud of Jake, who’s been working slavishly on this for a long time (he talks about the genesis of the project in this interview) as well as Francis, who wrote the film’s beautiful score.
If I never get to work on something cooler I’ll die happy.

Can’t wait to see this.

    jstn:

    Robot and Frank is the feature film debut of Jake Schreier, my friend and longtime Francis and the Lights co-conspirator (you may know him as the director of the incredible video for The Top). It stars Frank Langella as an old man with a slipping memory whose kids (James Marsden and Liv Tyler) give him a caretaker robot that he initially loathes but gradually forms an uneasy alliance with. It just premiered at Sundance this week (see some clips here) and will likely be coming soon to a theater near you.

    It also features a number of near-future devices with fictional user interfaces imagined and designed by myself, which was one of the funnest projects I’ve ever worked on. I have a new appreciation for the needs of a real, functioning interface versus the kind you see in the movies. I don’t want to spoil anything, but if you wind up seeing it keep an eye on Frank’s TV and everyone’s cell phones and tablets.

    So, clearly I’m biased, but I saw a rough cut of the movie a couple months back and truly loved it. I couldn’t be more proud of Jake, who’s been working slavishly on this for a long time (he talks about the genesis of the project in this interview) as well as Francis, who wrote the film’s beautiful score.

    If I never get to work on something cooler I’ll die happy.

    Can’t wait to see this.

    2138 notes    /   Comments    /   Reblogged 4 days ago from jstn
  • What really happens to our muscles as we age if we are chronically active?
These are MRI cross sections of leg muscles. Via this recently published study in the journal Physician and Sports Medicine. See also.

    What really happens to our muscles as we age if we are chronically active?

    These are MRI cross sections of leg muscles. Via this recently published study in the journal Physician and Sports Medicine. See also.

    341 notes    /   Comments    /   Posted 4 days ago
  • This looks great and it’s one of the most important health issues in our country. Glad to see there is more attention being given to why our cities and economy were designed to make health so hard.

    A provocative new 4-hour series soon to air on public television, Designing Healthy Communities, examines the impact of our built environment on key public health indices, including obesity, diabetes, heart disease, asthma, cancer and depression. The series documents the connection between bad community design and burgeoning health consequences, and discusses the remedies available to fix what has become an urgent crisis.

    Retrofitting Suburbia (by MPC)

    via

    90 notes    /   Comments    /   Posted 1 week ago from bookmarklet
  • Good news from a study just published in Circulation:

Sex is the cause of less than 1% of all acute heart attacks, the review said. And autopsy studies suggest that only between 0.6% and 1.7% of sudden deaths are related to sexual activity.
(A word to the wise for cheaters, though: Of those who did die during the act, most were men having “extramarital sexual activity, in most cases with a younger partner in an unfamiliar setting and/or after excessive food and alcohol consumption.”)
via

    Good news from a study just published in Circulation:

    Sex is the cause of less than 1% of all acute heart attacks, the review said. And autopsy studies suggest that only between 0.6% and 1.7% of sudden deaths are related to sexual activity.

    (A word to the wise for cheaters, though: Of those who did die during the act, most were men having “extramarital sexual activity, in most cases with a younger partner in an unfamiliar setting and/or after excessive food and alcohol consumption.”)

    via

    42 notes    /   Comments    /   Posted 1 week ago
  • by Jessica Hische

    by Jessica Hische

    86 notes    /   Comments    /   Posted 1 week ago
  • [Flash 9 is required to listen to audio.]

    A lovely, lovely song. Buy it here.

    The War on Drugs, Come to the City. This record has been on constant rotation for the last 4 months or so. And then seeing them open up for The National at the Beacon Theater, well, they are just spectacular.

    24 notes    /   Comments    /   Posted 1 week ago
  • strle:

superamit:

Many of you have asked, so here’s what’s going on with me.
WHAT HAPPENED BEFORE
8/1979: Born. Grew up in CT, built a killer eraser collection, fell in love with computers.
Left college to start a company. Fell hard. Fled to India for 3 months.
Started 2nd company. Learned to be an adult. Fell in love with NYC.
Moved to SF, discovered burritos & some of my fave people on Earth.
9/2011: Got diagnosed with Leukemia!
Cried. Went through 3 cycles of chemo. Hurt. Thought hard about what I want out of life. Grew up a second time.
TODAY
… After over 100 drives organized by friends, family, and strangers, celebrity call-outs, a bazillion reblogs (7000+!), tweets, and Facebook posts, press, fundraising and international drives organized by tireless friends, and a couple painful false starts, I’ve got a 10/10 matched donor!
You all literally helped save my life. (And the lives of many others.)
WHAT HAPPENS NEXT
Tomorrow, I’ll be admitted to Dana Farber in Boston for 4-5 weeks.
First I’ll get a second Hickman line to allow direct access to my heart (for meds and for nutrients if I’m not able to eat). Over the next week, the docs blast my body with a stiff chemo cocktail to try and eradicate all traces of cancer cells. In the process, the immune system I was born with, and my body’s ability to make blood, are destroyed.
Next Friday, I get my donor’s stem cells by IV. I start on immunosuppressants to prevent my body from rejecting them (I’ll be on them for 12-18 months). For these weeks I’ve no immune system, so I’m severely vulnerable to viruses and bacteria. My hospital room and hallway become my world.
Meanwhile, the stem cells make their way to my bone marrow and, with some luck, start producing platelets, red blood cells, and white blood cells. At this point, my blood type changes to the blood type of my donor. And my blood will now have my donor’s DNA, not my own.
This is science fiction stuff. I can hardly believe it’s even possible, and there’s lots of chances for things to go wrong. It’s frightening.
AFTER THE TRANSPLANT
Recovery to a new state of “normal” takes about a year, but there’s a few storm clouds hovering:
My immune system is new, like a baby’s. I’m prone to getting sick.
Just as with any organ transplant, there’s a chance of rejection. Except in this case, it’s my blood that’s the foreign body, and it touches every organ. They call it graft-vs-host-disease and it can cause health issues and organ complications for the rest of my life.
Successful transplant or not, Leukemia can relapse. Stubborn mofo.
Overall, 75% of AML transplant patients survive year one, 50% make it through year five. My odds are a little better since I’m young.
THE GREAT NEWS
I’ve got a long road ahead. But I’ve got a donor & amazing family & friends. A few months ago I didn’t have many options. Today I have a plan.
I am alive. I start tomorrow. Wish me luck!
Thank you.

<3

    strle:

    superamit:

    Many of you have asked, so here’s what’s going on with me.

    WHAT HAPPENED BEFORE

    • 8/1979: Born. Grew up in CT, built a killer eraser collection, fell in love with computers.
    • Left college to start a company. Fell hard. Fled to India for 3 months.
    • Started 2nd company. Learned to be an adult. Fell in love with NYC.
    • Moved to SF, discovered burritos & some of my fave people on Earth.
    • 9/2011: Got diagnosed with Leukemia!
    • Cried. Went through 3 cycles of chemo. Hurt. Thought hard about what I want out of life. Grew up a second time.

    TODAY

    … After over 100 drives organized by friends, family, and strangers, celebrity call-outs, a bazillion reblogs (7000+!), tweets, and Facebook posts, press, fundraising and international drives organized by tireless friends, and a couple painful false starts, I’ve got a 10/10 matched donor!

    You all literally helped save my life. (And the lives of many others.)

    WHAT HAPPENS NEXT

    Tomorrow, I’ll be admitted to Dana Farber in Boston for 4-5 weeks.

    First I’ll get a second Hickman line to allow direct access to my heart (for meds and for nutrients if I’m not able to eat). Over the next week, the docs blast my body with a stiff chemo cocktail to try and eradicate all traces of cancer cells. In the process, the immune system I was born with, and my body’s ability to make blood, are destroyed.

    Next Friday, I get my donor’s stem cells by IV. I start on immunosuppressants to prevent my body from rejecting them (I’ll be on them for 12-18 months). For these weeks I’ve no immune system, so I’m severely vulnerable to viruses and bacteria. My hospital room and hallway become my world.

    Meanwhile, the stem cells make their way to my bone marrow and, with some luck, start producing platelets, red blood cells, and white blood cells. At this point, my blood type changes to the blood type of my donor. And my blood will now have my donor’s DNA, not my own.

    This is science fiction stuff. I can hardly believe it’s even possible, and there’s lots of chances for things to go wrong. It’s frightening.

    AFTER THE TRANSPLANT

    Recovery to a new state of “normal” takes about a year, but there’s a few storm clouds hovering:

    • My immune system is new, like a baby’s. I’m prone to getting sick.
    • Just as with any organ transplant, there’s a chance of rejection. Except in this case, it’s my blood that’s the foreign body, and it touches every organ. They call it graft-vs-host-disease and it can cause health issues and organ complications for the rest of my life.
    • Successful transplant or not, Leukemia can relapse. Stubborn mofo.

    Overall, 75% of AML transplant patients survive year one, 50% make it through year five. My odds are a little better since I’m young.

    THE GREAT NEWS

    I’ve got a long road ahead. But I’ve got a donor & amazing family & friends. A few months ago I didn’t have many options. Today I have a plan.

    I am alive. I start tomorrow. Wish me luck!

    Thank you.

    <3

    8420 notes    /   Comments    /   Reblogged 1 week ago from strle
  • apoplecticskeptic:

@Skulled
via @vincelavecchia

So good&#8230;

    apoplecticskeptic:

    @Skulled

    via @vincelavecchia

    So good…

    706 notes    /   Comments    /   Reblogged 1 week ago from evangotlib
  • Christopher Lyles, 30, had tracheal cancer that had progressed so far it was considered inoperable. In November, doctors made him a new windpipe - or trachea - made out of tiny plastic fibers seeded with stem cells from his own bone marrow.

Two months after his successful operation, Lyles arrived home in Md. last week.

via

    Christopher Lyles, 30, had tracheal cancer that had progressed so far it was considered inoperable. In November, doctors made him a new windpipe - or trachea - made out of tiny plastic fibers seeded with stem cells from his own bone marrow.

    Two months after his successful operation, Lyles arrived home in Md. last week.

    via

    240 notes    /   Comments    /   Posted 1 week ago
  • The New York Times is reporting that the MTA is reassessing the width of its&#8217; seats on public transit to account for our nation&#8217;s ever increasing backsides.
It&#8217;s interesting how our country is being redesigned for the new normal. Every industry is making their own rules&#8212; the airlines make obese people buy two seats for example. 
But the one thing that frustrates me about the airlines is the policy charging passengers for luggage based on weight:

Me: 159 pounds + 55 pound suitcase
Guy in front of me: 300 pounds + 45 pound suitcase

I get charged a hefty weight fine because my suitcase is 5 pounds overweight. If airlines are going to charge us for the weight of our luggage, they should assess our total weight, not just the weight of our luggage. It&#8217;s only fair.

    The New York Times is reporting that the MTA is reassessing the width of its’ seats on public transit to account for our nation’s ever increasing backsides.

    It’s interesting how our country is being redesigned for the new normal. Every industry is making their own rules— the airlines make obese people buy two seats for example. 

    But the one thing that frustrates me about the airlines is the policy charging passengers for luggage based on weight:

    Me: 159 pounds + 55 pound suitcase

    Guy in front of me: 300 pounds + 45 pound suitcase

    I get charged a hefty weight fine because my suitcase is 5 pounds overweight. If airlines are going to charge us for the weight of our luggage, they should assess our total weight, not just the weight of our luggage. It’s only fair.

    228 notes    /   Comments    /   Posted 1 week ago
  • I took a trip to Philadelphia yesterday to take a tour of Eastern State Penitentiary. It was built in 1829 and became known as the most influential prison in both design and strategy in the entire world. It was the first large building in the United States to have central heating and running water. Of course, neither worked really well&#8212; toilets were flushed by the guards only a few times a week. One guard could see down all seven of the hallways at one time due to it&#8217;s hub and spoke design and mirrors. It looks like a castle and was built 2 and a half miles outside of Philadelphia&#8217;s city center at the time. The spooky castle on a hill was designed to intimate the population into behaving well.
It housed 250 prisoners in 250 cells, in solitary confinement for typical sentences of 2 to 6 years. The most common crime was horse theft. The root word of penitentiary is penance. It was thought that if you put criminals in solitary confinement in a church-like setting, they will have nothing else to think about but remorse and Jesus. They also taught the criminals a trade, like boot-making, so when they got out they could be productive members of society. It even had its own hospital. Contraband was typically smuggled in from outsiders throwing hollowed out baseballs over the walls.
As time went by the penitentiary suffered from overcrowding, riots, disease, and encroachment by the city. It was finally shut down in 1971.
The designers of this prison tried to solve multiple societal problems&#8212; how to rehabilitate criminals, how to design a physical place that would foster rehabilitation, and how to prevent criminality. The person that designed this was a genius&#8212; not because of his theories on criminality, but because he actually got this thing built. The White House in 1829 didn&#8217;t even have running water. But the prison on a hill for 250 criminals outside Philadelphia did. Imagine the politics of that simple statement.
It&#8217;s almost 200 years later, and our solution is to throw 3% of our population in privatized prisons and expect that they&#8217;ll just get better. In 1829, the entire state of Pennsylvania had 1.35 million people. And only 250 people in its state prison, most doing time for horse theft. Given today&#8217;s rate of 3%, they should have built a prison for 40,500 people.
The issue that hit me the hardest was that in 1829 criminologists were dealing with the exact same issues as we are today&#8212; how best to rehabilitate criminals. We&#8217;ve got the world&#8217;s knowledge at our fingertips, but have very little idea how to fix crime. It&#8217;s a big fat hairy problem. And 200 years later, we&#8217;re really no closer to the solution than we were in 1829. In fact, it&#8217;s worse. The rates of criminality needing rehabilitation are astronomically higher.
How many other problems in our society will we be no closer to the solution 200 years from now? How to deliver equitable healthcare to a population of diverse people? How to educate our children? As an optimistic curmudgeon, I&#8217;ve always believed in humans&#8217; ability to solve problems. But what if the last 20% of big fat hairy problems are unsolveable because they&#8217;re politically motivated human behavior problems? 
The real issue is that these issues can&#8217;t be solved with theories. They can only be moved along every so often with politics and cultural changes. Two hundred years, on the grand scale of things, isn&#8217;t that long. It&#8217;s a few generations. We, hopefully, all play our part in helping society progress. But our lives are just so, so short. I recently talked with someone who said, if you&#8217;re an entrepreneur, you should find an idea, build it out, and spend at least 5 years fully dedicated to that idea. At the end of five years, if the idea is working or not working, move on to the next big one. That means, if a typical person works 45 years, they have nine ideas they will work on in their lifetime.
Nine. It isn&#8217;t that large of a number. And of those nine, how many of your ideas will truly impact society for the better?  

    I took a trip to Philadelphia yesterday to take a tour of Eastern State Penitentiary. It was built in 1829 and became known as the most influential prison in both design and strategy in the entire world. It was the first large building in the United States to have central heating and running water. Of course, neither worked really well— toilets were flushed by the guards only a few times a week. One guard could see down all seven of the hallways at one time due to it’s hub and spoke design and mirrors. It looks like a castle and was built 2 and a half miles outside of Philadelphia’s city center at the time. The spooky castle on a hill was designed to intimate the population into behaving well.

    It housed 250 prisoners in 250 cells, in solitary confinement for typical sentences of 2 to 6 years. The most common crime was horse theft. The root word of penitentiary is penance. It was thought that if you put criminals in solitary confinement in a church-like setting, they will have nothing else to think about but remorse and Jesus. They also taught the criminals a trade, like boot-making, so when they got out they could be productive members of society. It even had its own hospital. Contraband was typically smuggled in from outsiders throwing hollowed out baseballs over the walls.

    As time went by the penitentiary suffered from overcrowding, riots, disease, and encroachment by the city. It was finally shut down in 1971.

    The designers of this prison tried to solve multiple societal problems— how to rehabilitate criminals, how to design a physical place that would foster rehabilitation, and how to prevent criminality. The person that designed this was a genius— not because of his theories on criminality, but because he actually got this thing built. The White House in 1829 didn’t even have running water. But the prison on a hill for 250 criminals outside Philadelphia did. Imagine the politics of that simple statement.

    It’s almost 200 years later, and our solution is to throw 3% of our population in privatized prisons and expect that they’ll just get better. In 1829, the entire state of Pennsylvania had 1.35 million people. And only 250 people in its state prison, most doing time for horse theft. Given today’s rate of 3%, they should have built a prison for 40,500 people.

    The issue that hit me the hardest was that in 1829 criminologists were dealing with the exact same issues as we are today— how best to rehabilitate criminals. We’ve got the world’s knowledge at our fingertips, but have very little idea how to fix crime. It’s a big fat hairy problem. And 200 years later, we’re really no closer to the solution than we were in 1829. In fact, it’s worse. The rates of criminality needing rehabilitation are astronomically higher.

    How many other problems in our society will we be no closer to the solution 200 years from now? How to deliver equitable healthcare to a population of diverse people? How to educate our children? As an optimistic curmudgeon, I’ve always believed in humans’ ability to solve problems. But what if the last 20% of big fat hairy problems are unsolveable because they’re politically motivated human behavior problems? 

    The real issue is that these issues can’t be solved with theories. They can only be moved along every so often with politics and cultural changes. Two hundred years, on the grand scale of things, isn’t that long. It’s a few generations. We, hopefully, all play our part in helping society progress. But our lives are just so, so short. I recently talked with someone who said, if you’re an entrepreneur, you should find an idea, build it out, and spend at least 5 years fully dedicated to that idea. At the end of five years, if the idea is working or not working, move on to the next big one. That means, if a typical person works 45 years, they have nine ideas they will work on in their lifetime.

    Nine. It isn’t that large of a number. And of those nine, how many of your ideas will truly impact society for the better?  

    73 notes    /   Comments    /   Posted 1 week ago
  • Molecular visualizations of DNA. Stunning. Especially replication, which begins at 1:42.

    347 notes    /   Comments    /   Posted 1 week ago
  • thingsorganizedneatly:

SUBMISSION: physician paraphernalia, circa 1940

    thingsorganizedneatly:

    SUBMISSION: physician paraphernalia, circa 1940

    664 notes    /   Comments    /   Reblogged 2 weeks ago from thingsorganizedneatly
  • Please read all of this, especially if you&#8217;re a parent.
How To Land Your Kid in Therapy:

MY FIRST SEVERAL patients were what you might call textbook. As they shared their histories, I had no trouble making connections between their grievances and their upbringings. But soon I met a patient I’ll call Lizzie. Imagine a bright, attractive 20-something woman with strong friendships, a close family, and a deep sense of emptiness. She had come in, she told me, because she was “just not happy.” And what was so upsetting, she continued, was that she felt she had nothing to be unhappy about. She reported that she had “awesome” parents, two fabulous siblings, supportive friends, an excellent education, a cool job, good health, and a nice apartment. She had no family history of depression or anxiety. So why did she have trouble sleeping at night? Why was she so indecisive, afraid of making a mistake, unable to trust her instincts and stick to her choices? Why did she feel “less amazing” than her parents had always told her she was? Why did she feel “like there’s this hole inside” her? Why did she describe herself as feeling “adrift”?
I was stumped. Where was the distracted father? The critical mother? Where were the abandoning, devaluing, or chaotic caregivers in her life?
As I tried to make sense of this, something surprising began happening: I started getting more patients like her. Sitting on my couch were other adults in their 20s or early 30s who reported that they, too, suffered from depression and anxiety, had difficulty choosing or committing to a satisfying career path, struggled with relationships, and just generally felt a sense of emptiness or lack of purpose—yet they had little to quibble with about Mom or Dad.
Instead, these patients talked about how much they “adored” their parents. Many called their parents their “best friends in the whole world,” and they’d say things like “My parents are always there for me.” Sometimes these same parents would even be funding their psychotherapy (not to mention their rent and car insurance), which left my patients feeling both guilty and utterly confused. After all, their biggest complaint was that they had nothing to complain about!

Portrait by me

    Please read all of this, especially if you’re a parent.

    How To Land Your Kid in Therapy:

    MY FIRST SEVERAL patients were what you might call textbook. As they shared their histories, I had no trouble making connections between their grievances and their upbringings. But soon I met a patient I’ll call Lizzie. Imagine a bright, attractive 20-something woman with strong friendships, a close family, and a deep sense of emptiness. She had come in, she told me, because she was “just not happy.” And what was so upsetting, she continued, was that she felt she had nothing to be unhappy about. She reported that she had “awesome” parents, two fabulous siblings, supportive friends, an excellent education, a cool job, good health, and a nice apartment. She had no family history of depression or anxiety. So why did she have trouble sleeping at night? Why was she so indecisive, afraid of making a mistake, unable to trust her instincts and stick to her choices? Why did she feel “less amazing” than her parents had always told her she was? Why did she feel “like there’s this hole inside” her? Why did she describe herself as feeling “adrift”?

    I was stumped. Where was the distracted father? The critical mother? Where were the abandoning, devaluing, or chaotic caregivers in her life?

    As I tried to make sense of this, something surprising began happening: I started getting more patients like her. Sitting on my couch were other adults in their 20s or early 30s who reported that they, too, suffered from depression and anxiety, had difficulty choosing or committing to a satisfying career path, struggled with relationships, and just generally felt a sense of emptiness or lack of purpose—yet they had little to quibble with about Mom or Dad.

    Instead, these patients talked about how much they “adored” their parents. Many called their parents their “best friends in the whole world,” and they’d say things like “My parents are always there for me.” Sometimes these same parents would even be funding their psychotherapy (not to mention their rent and car insurance), which left my patients feeling both guilty and utterly confused. After all, their biggest complaint was that they had nothing to complain about!

    Portrait by me

    119 notes    /   Comments    /   Posted 2 weeks ago
  • Hostess, maker of Twinkies, files for bankruptcy.
Meanwhile, restaurants like Le Pain Quotidien and shares of Whole Foods and Lululemon are on the rise. This is capitalism at its best, and one of the main reasons why I&#8217;m optimistic about our nation&#8217;s health. You&#8217;ve got to fight capitalism with capitalism.

    Hostess, maker of Twinkies, files for bankruptcy.

    Meanwhile, restaurants like Le Pain Quotidien and shares of Whole Foods and Lululemon are on the rise. This is capitalism at its best, and one of the main reasons why I’m optimistic about our nation’s health. You’ve got to fight capitalism with capitalism.

    116 notes    /   Comments    /   Posted 2 weeks ago
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